Principal Scientist, Peptide Early Portfolio and Platform (PEPP) Lead - Global Discovery Chemistry
Company: Disability Solutions
Location: Spring House
Posted on: April 20, 2024
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Job Description:
Johnson & Johnson is recruiting for a Principal Scientist,
Peptide Early Portfolio and Platform (PEPP) Lead - Global Discovery
Chemistry, located in Spring House, PA. About Johnson & Johnson At
Johnson & Johnson, we believe health is everything. Our strength in
healthcare innovation empowers us to build a world where complex
diseases are prevented, treated, and cured, where treatments are
smarter and less invasive, and solutions are personal. Through our
expertise in Innovative Medicine and MedTech, we are uniquely
positioned to innovate across the full spectrum of healthcare
solutions today to deliver the breakthroughs of tomorrow, and
profoundly impact health for humanity. Learn more at Global
Discovery Chemistry is an integral and growing part of the Johnson
& Johnson Innovative Medicine Therapeutics Discovery (TD)
organization, which is committed to the delivery of high-quality
drug candidates in partnership with all Therapeutic Area (TA)
discovery organizations. The Therapeutics Discovery (TD)
organization's mission requires deep scientific expertise in
multiple disciplines including chemistry, cellular and molecular
pharmacology, enzymology, and screening technologies coupled with
an ability to work collaboratively with internal and external
organizations, including the discovery facing development teams
Discovery Product Research (DPR) and Developability. Building on a
strong legacy of success, we are currently recruiting an
outstanding individual to join our Spring House, Pennsylvania,
based team as Peptide Early Portfolio and Platform (PEPP) Lead,
Global Discovery Chemistry - a role that offers tremendous growth
opportunity within a dynamic and science-driven organization.
Located in suburban Philadelphia, the Johnson & Johnson Innovative
Medicine Spring House campus sits at the heart of the thriving
mid-Atlantic biopharmaceutical belt, offering easy access to some
of nation's premiere educational, research, and medical centers of
excellence. We are seeking a highly skilled and motivated chemist
with extensive peptide chemistry knowledge, mRNA display peptide
discovery platform and medicinal chemistry expertise to lead our
Peptide Early Portfolio and Platform (PEPP) team in Global
Discovery Chemistry. This position will require the candidate to
possess and leverage deep knowledge and capabilities to discover
differentiated peptides for J&J targets within our Disease and
Pathway Area Stronghold (DAS and PAS) strategy. Using a mix of
internal and external resources, the incumbent will partner with
key stakeholders in the Therapeutic Areas, Discovery Technology and
Molecular Pharmacology (DTMP) and other internal groups, represent
medicinal chemistry, lead cross-functional mRNA display peptide
discovery platform, and be co-responsible for target selection,
design of screening, mRNA display screen, hits resynthesis and
optimization with Hit-to-Lead entry as the deliverable. Candidates
with deep expertise in peptide hit identification platforms
including phage and mRNA display, optimization using
state-of-the-art peptide synthetic chemistry and computational
methods are encouraged to apply. Candidates with experience in
advancing peptide programs from hits to preclinical candidate and
various peptide drug delivery strategies are preferred.
Responsibilities of the Principal Scientist, PEPP Lead will
include:
Keywords: Disability Solutions, Lower Merion , Principal Scientist, Peptide Early Portfolio and Platform (PEPP) Lead - Global Discovery Chemistry, Other , Spring House, Pennsylvania
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